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In this original research published in Science on May 20th, 9 rhesus macaques were infected with SARS-CoV-2 virus and developed an interstitial viral pneumonia, mimicking the human clinical course. All animals survived, and 35 days later the same animals were inoculated again with the same exposure to SARS-CoV-2 virus. Extensive immunologic testing demonstrated robust immune response in the rhesus macaques and none of animals developed recurrent clinical symptoms. This is an extremely important finding for two reasons. First, it demonstrates that the rhesus macaque may be an important scientific model for human disease and an important platform for further immunologic research. Second, this is one of the first prospective controlled studies demonstrating that infection with SARS-CoV-2 virus can induce appropriate immune response and subsequent immunity. In short, this is a small but very promising study showing that getting sick with COVID-19 may offer strong protection from future exposure.
Please click here to see the original article in the journal Science.