In this observational study of 1446 patients with COVID-19 admitted to a large New York City medical center, no benefit was found for those treated with hydroxychloroquine. Hydroxychloroquine has been widely touted as a treatment for COVID-19 but the data for its effectiveness has been unclear. This retrospective study examined hospitalized patients that were treated with hydroxychloroquine vs. those that were not and compared rates of respiratory failure requiring intubation and death. When controlled for disease severity, there was found to be no difference between the two groups. This is very important data suggesting that the use of hydroxychloroquine is likely ineffective at altering important outcomes in COVID-19. Prospective randomized control trials are currently underway to further confirm this finding.
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